By I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins
''...the quantity surely succeeds total as an in-depth survey of either the biology and the biochemistry of a ubiquitous and astonishingly various kinfolk of very advanced enzymes. each workforce with an curiosity in those proteins should still personal a copy.'' -CELL (July 2003) ''The editors of ABC Proteins: From micro organism to Man have valiantly tried to surround during this quantity the total scope of analysis on those proteins, from atomic-resolution constitution to human genetic ailments, and from Escherichia coli to Homo sapiens and Arabidopsis thaliana... What the ebook makes seen is that just about all ABC proteins are membrane localized, ATP based, basic lively transporters...In addition to advances in our figuring out of ABC transporter constitution, a number of chapters within the publication additionally describe development that has been made in elcuidating the mechanisms of shipping. the amount absolutely succeeds total as an in-depth survey of either the biology and the biochemistry of a ubiquitous and astoundingly different kinfolk of very complicated enzymes. each workforce with an curiosity in those proteins may still personal a replica. ultimately, this e-book makes a resounding case that many laboratories that will not but suspect it's going to quickly have a way more abiding curiosity in ABC proteins.'' ''...well equipped and incorporated fantastically transparent colour pictures and figures.'' -E STREAMS (July 2003)
Read or Download ABC Proteins. From Bacteria to Man PDF
Best basic science books
A legitimate and certain wisdom of the anatomy of the pelvic flooring is of the maximum significance to gynecologists, obstetricians, surgeons, and urologists, given that all of them proportion an analogous accountability in treating sufferers with diverse pathological stipulations as a result of pelvic ground disorder. the commonest medical expressions of pelvic flooring disorder are urinary incontinence, anal incontinence, and pelvic organ prolapse.
Facioscapulohumeral muscular dystrophy (FSHD) is a genetic ailment regarding slowly innovative muscle degeneration during which the muscle tissues of the face, shoulder blades and top hands are one of the so much critically affected. it's the 3rd commonest inherited muscular dystrophy, affecting 1 in 20,000. the quest for the molecular foundation of the ailment is of curiosity to all genetic researchers, related to a deletion outdoors a coding quarter leading to over-expression of adjoining genes.
This booklet is the 1st to target potassium ion channels and covers the hot striking growth made in study on those proteins. Many illnesses are as a result of the abnormalities of potassium ion channels. They comprise diabetes mellitus, life-threatening hereditary cardiac arrhythmia, epilepsy, neural degeneration, and renal high blood pressure.
Elsevier now bargains a sequence of spinoff works in keeping with the acclaimed Meyler's aspect impression of substances, fifteenth variation. those person volumes are grouped by means of forte to learn the practising biomedical researcher and/or clinician. there was major development within the improvement of unique treatment medicines that act in particular on convinced cancers, and that reduce harm to general cells.
Additional info for ABC Proteins. From Bacteria to Man
Microbiol. 152, 291–301. , Hofnung, M. H. (1995) Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases. Res. Microbiol. 146, 271–278. D. S. (1993) Component A2 of methylcoenzyme M reductase system from Methanobacterium thermoautotrophicum delta H: nucleotide sequence and functional expression by Escherichia coli. J. Bacteriol. 175, 3195–3203. S. and Keinanen, K. (1998) AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition.
Barnes, R. H. (2000) Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290, 1771–1775. , Distler, J. and Piepersberg, W. 0 (ETH 22794): new operons and evidence for pathway-specific regulation by StrR. Mol. Gen. Genet. 250, 775–784. , Lebleu, B. and Salehzada, T. (1995) Cloning and characterization of a RNAse L inhibitor. A new component of the interferon-regulated 2-5A pathway. J. Biol. Chem. 270, 13308–13317. , Le Roy, F. and Salehzada, T.
W. (1993) Cloning of an M. tuberculosis DNA fragment associated with entry and survival inside cells. Science 261, 1454–1457. H. (2000). The beta-cell K-ATP channel. J. Membr. Biol. 176, 187–206. M. H. (1997) The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt’s disease (ABCR). FEBS Lett. 409, 247–252. , et al. (1998) Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain. J. Biol. Chem. 273, 32167–32175. , Wolfger, H.
ABC Proteins. From Bacteria to Man by I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins